Giant proliferating pilomatricoma; report of a rare entity.

Proliferating pilomatricoma is a benign tumour and a rare variant of pilomatricoma that has the potential for local recurrence if incompletely excised. We report a case of giant proliferating pilomatricoma on the forearm of a 66-year-old woman. This tumour was unusually large and the presence of ulceration and rapid growth raised clinical suspicion of malignancy. The identification of shadow or ghost cells is a good clue to matrical differentiation, which can be confirmed by β-catenin immunostaining.

as reported in: Grohs RL, Mesbah Ardakani N, Harvey NT, Luczak BP, Wood BA. Australas. J. Dermatol.. 2016 Jun:. doi: 10.1111/ajd.12512.
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